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SCIENTIFIC AGENDA

CLINICAL TRACK   |   RESEARCH TRACK   |   SATELLITE SYMPOSIA

CLINICAL
Friday, December 5, 2008

7:00 am
Breakfast

8:00 am
Welcome and introduction
Stephen B. Hanauer, MD and Richard P. MacDermott, MD

Session I A : Advances in clinical IBD–I
Moderators: Russell D. Cohen, MD and Bruce E. Sands, MD

8:10 am
Use of mesalamine products, antibiotics and steroids in IBD
David T. Rubin, MD

8:30 am
Use of immunomodulators in IBD
Daniel H. Present, MD

8:50 am
Current biologic therapies in IBD
Stephen B. Hanauer, MD

9:10 am
Future therapies in IBD
William J. Sandborn, MD

9:30 am
Panel discussion

10:00 am
Coffee break and poster viewing

*Session II A: Advances in clinical IBD–II
Moderators: Stephen B. Hanauer, MD and William J. Sandborn, MD

10:30 am
Perianal disease and fistulae in Crohn’s disease
David A. Schwartz, MD

10:50 am
Advances in surgery in IBD
Scott A. Strong, MD

11:10 am
Prevention and management of postoperative Crohn’s disease
Miguel Regueiro, MD

11:30 am
Diagnosis and management of Crohn’s disease of the ileoanal pouch
Bo Shen, MD

11:50 am
Panel discussion

12:20 pm
Lunch break

*Session III A: Case based Clinical break-out sessions
All talks are 45 minutes, begin at 2:00 pm and repeat at 3:00 pm
2:00 pm

Colon cancer surveillance and prevention in IBD
David T. Rubin, MD and Fernando S. Velayos, MD, MPH

Nutritional issues in IBD
Arthur D. Heller, MD and Joseph H. Sellin, MD
Treatment of extraintestinal manifestations in IBD
Robert Burakoff, MD and Bret A. Lashner, MD
Treatment of ostomy and post-surgical problems in IBD
Jan Colwell, RN, MS, CWOCN and Scott A. Strong, MD
Healthcare maintenance in patients with IBD
Sunanda V. Kane, MD and Uma Mahadevan, MD

2:45 pm—Move to second breakout

3:00 pm

Colon cancer surveillance and prevention in IBD
David T. Rubin, MD and Fernando S. Velayos, MD, MPH

Nutritional issues in IBD
Arthur D. Heller, MD and Joseph H. Sellin, MD
Treatment of extraintestinal manifestations in IBD
Robert Burakoff, MD and Bret A. Lashner, MD
Treatment of ostomy and post-surgical problems in IBD
Jan Colwell, RN, MS, CWOCN and Scott A. Strong, MD
Healthcare maintenance in patients with IBD
Sunanda V. Kane, MD and Uma Mahadevan, MD

3:45 pm
Coffee break and poster viewing

*Session IV A: Original clinical research scientific presentations–I
Moderators: Peter Higgins, MD, PhD and Edward V. Loftus Jr., MD

4:00 pm
Presentation of clinical research abstracts

*Session IV C: IBD Nursing Session
Moderators: Jan Colwell, RN, MS, CWOCN, FAAN

4:00 pm
Management of the patient with a fistula
Margaret Goldberg, RN, MS, CWOCN

4:20 pm
Ileal pouch anal anastomosis: Understanding the procedure and issues in patient management
Michele Rubin, APN, CNS-BC,CGRN

4:40 pm
Living with inflammatory bowel disease: A patient’s perspective
Tammy Poma, APN-BC, CNN

5:00 pm
Interactive case studies

5:20 pm
Panel discussion

5:30 pm
Adjourn

SATURDAY, DECEMBER 6, 2008

8:00 am
Welcome and introduction
Stephen B. Hanauer, MD and Richard P. MacDermott, MD

*Session V A: Advances in the management of IBD–I
Moderators: Asher A. Kornbluth, MD and Gary R. Lichtenstein, MD

8:10 am
Communicating risks and benefits to IBD patients
Corey A. Siegel, MD

8:30 am
Clostridia difficile infections in IBD patients
David G. Binion, MD

8:50 am
Gender related issues in the female with IBD
Sunanda V. Kane, MD

9:10 am
Gender related issues in the male with IBD
Uma Mahedevan, MD

9:30 am
Panel discussion

10:00 am
Coffee break and poster viewing

Session V C: Pediatric IBD
Moderators: Athos Bousvaros, MD and Joel R. Rosh, MD

8:10 am
Differentiating Crohn’s disease from ulcerative colitis in pediatric IBD
Athos Bousvaros, MD

8:30 am
Sexuality and other challenges for adolescents with IBD
Marla C. Dubinsky, MD

8:50 am
Use of biologic therapies in pediatrics
Robert N. Baldassano, MD

9:10 am
Risk and prevention of lymphomas in pediatric IBD
Joel R. Rosh, MD

9:30 am
Panel discussion

10:00 am
Coffee break and poster viewing

*Session VI A: Debates: Current controversies in IBD
Moderators: Marla C. Dubinsky, MD and William J. Tremaine, MD

10:30 am
Pro: Biologics should be used before immunomodulators in ulcerative colitis
and in Crohn’s disease
Stephen B. Hanauer, MD

10:50 am
Con: Immunomodulators should be used before biologics in ulcerative colitis
and in Crohn’s disease
Gary R. Lichtenstein, MD

11:10 am
Panel discussion

11:30 am
Pro: Chemoendoscopy or narrow band imaging with targeted biopsies should
be the cancer surveillance endoscopy procedure of choice in ulcerative colitis
Bret A. Lashner, MD

11:50 am
Con: Colonoscopy with at least 30 biopsies should be the cancer surveillance
endoscopy procedure of choice in ulcerative colitis
Asher A. Kornbluth, MD

12:10 pm
Panel discussion

12:20 pm
Lunch break

*Session VII A: Case-based break-out sessions
All talks are 45 minutes, begin at 2:00 pm and repeat at 3:00 pm

2:00 pm

Use and misuse of serologic biomarkers and 6-MP metabolites in IBD
Maria T. Abreu, MD and Marla C. Dubinsky, MD

Challenges in treating the adolescent with IBD
Robert N. Baldassano, MD and Joel R. Rosh, MD
Diagnosis, treatment and prevention of infectious complications of IBD
Bruce E. Sands, MD and Corey A. Siegel, MD
Dealing with disability issues in IBD
Russell D. Cohen, MD and Joseph H. Sellin, MD
Ethical issues in the care of patients with IBD
David T. Rubin, MD and William J. Tremaine, MD

2:45 pm— Move to second breakout

2:00 pm

Use and misuse of serologic biomarkers and 6-MP metabolites in IBD
Maria T. Abreu, MD and Marla C. Dubinsky, MD

Challenges in treating the adolescent with IBD
Robert N. Baldassano, MD and Joel R. Rosh, MD
Diagnosis, treatment and prevention of infectious complications of IBD
Bruce E. Sands, MD and Corey A. Siegel, MD
Dealing with disability issues in IBD
Russell D. Cohen, MD and Joseph H. Sellin, MD
Ethical issues in the care of patients with IBD
David T. Rubin, MD and William J. Tremaine, MD

3:45 pm— Break-out sessions end

*Session VIII A: Advances in the management of IBD–II
Moderators: Bret A. Lashner and Darrell S. Pardi, MD

4:00 pm
Can we afford to use the new IBD therapies?
Russell D. Cohen, MD

4:20 pm
The extra-algorithmic treatment of IBD: Options before and after standard approaches
William J. Tremaine, MD

4:40 pm
Diagnosis and treatment of IBS in the IBD patient
Richard P. MacDermott, MD

5:00 pm
Bone health in children and adults with IBD
Francisco A. Sylvester, MD

5:20 pm
Panel discussion

5:40 pm
Adjourn

Session VIII C: IBD Nursing Session (parallel with VIII A and VIII B)
Moderator: Jan Colwell, RN, MS, CWOCN, FAAN

4:00 pm
Growing up with IBD
Susan Peck, MSN, CRNP

4:20 pm
Alliance not compliance
Sharon Dudley Brown, PhD, FNP- BC

4:40 pm
Nutrition management of patients with IBD
Andrea Kozak, RD, LD

5:00 pm
Interactive case studies

5:20 pm
Panel discussion

5:30 pm
Adjourn

SUNDAY, DECEMBER 7, 2008
7:00 am
Breakfast

8:00 am
Welcome and introduction
Stephen B. Hanauer, MD and Richard P. MacDermott, MD

*Session IX A: Selected clinical topics in IBD
Moderators: David A. Schwartz, MD and Corey A. Siegel, MD

8:10 am
Relevance of epidemiology to the practice of IBD
Bruce E. Sands, MD

8:30 am
Natural history and risk stratification in IBD
Edward V. Loftus, Jr., MD

8:50 am
Practical approaches to the differential diagnosis of IBD
Peter Higgins, MD, PhD

9:10 am
Microscopic colitis
Darrell S. Pardi, MD

9:30 am
Panel discussion

10:00 am
Coffee break

Session X A: Original clinical research scientific presentations–II
Moderators: Joseph H. Sellin, MD and Fernando S. Velayos, MD, MPH

10:30 am
Presentation of clinical abstracts

12:00 pm
Summary and adjourn
Joseph H. Sellin, MD and Fernando S. Velayos, MD, MPH

RESEARCH TRACK
FRIDAY, DECEMBER 5, 2008

7:00 am
Breakfast

8:00 am
Welcome and introduction
Lloyd Mayer, MD and R. Balfour Sartor, MD

*Session I B: State-of-the-art in genetics of IBD
Moderators: Richard H. Duerr, MD and John D. Rioux, PhD

8:10 am
Ulcerative colitis loci identified in genome-wide association studies
Richard H. Duerr, MD

8:30 am
Genes common to autoimmune/inflammatory disorders
John D. Rioux, PhD

8:50 am
Functional roles of autophagy genes in IBD
Ramnik J. Xavier, MD

9:10 am
Functional roles of Nod2 in IBD
Clara Abraham, MD

9:30 am
Panel discussion

10:00 am
Coffee break and poster viewing

*Session II B: Basic research meet-the-professor seminars
All talks are 40 minutes, begin at 10:30 am and repeat at 11:30 am

10:30 am

Unanswered research questions regarding cells which
mediate inflammation
Hans-Christian Reinecker, MD, PhD and Scott B. Snapper, MD, PhD

Unanswered research questions in IBD genetics
Richard H. Duerr, MD and John D. Rioux, PhD
Unanswered research questions in innate immunity
Maria T. Abreu, MD and R. Balfour Sartor, MD

11:15 am—Move to second breakout

11:30 am

Unanswered research questions regarding cells which mediate inflammation
Hans-Christian Reinecker, MD, PhD and Scott B. Snapper, MD, PhD

Unanswered research questions in IBD genetics
Richard H. Duerr, MD and John D. Rioux, PhD
Unanswered research questions in innate immunity
Maria T. Abreu, MD and R. Balfour Sartor, MD

12:20 pm
Lunch break

*Session III B: State-of-the-art in microbiology of IBD
Moderators: Charles O. Elson, III, MD and R. Balfour Sartor, MD

2:00 pm
Advances in microbiology research in IBD
R. Balfour Sartor, MD

2:20 pm
The role of bacterial flagellins in IBD
Charles O. Elson III, MD

2:40 pm
Understanding epithelial cell-bacterial interactions in IBD
Wayne I. Lencer, MD

3:00 pm
Are there colitogenic bacteria in IBD?
Wendy Garrett, MD, PhD

3:20 pm
Panel discussion

3:45 pm
Coffee break and poster viewing

*Session IV B: Basic research scientific presentations–I
Moderators: Christian Jobin, PhD and Scott B. Snapper, MD, PhD

4:00 pm
Presentation of basic science research abstracts

5:30 pm
Adjourn

8:00 am
Welcome and introduction

*Session V B: State-of-the-art in immunology of IBD–I
Moderators: Maria T. Abreu, MD and Lloyd Mayer, MD

8:10 am
What is the role of the epithelial cell in IBD pathogenesis?
Lloyd Mayer, MD

8:30 am
What is the role of innate immune system research in IBD?
Maria T. Abreu, MD

8:50 am
What is the role of adaptive immune system research in IBD?
Scott E. Plevy, MD

9:10 am
What is the role of dendritic cells in IBD?
Hans-Christian Reinecker, MD, PhD

9:30 am
Panel discussion

10:00 am
Coffee break and poster viewing

*Session VI B: Basic research meet-the-professor seminars
All talks are 40 minutes, begin at 10:30 am and repeat at 11:30 am

10:30 am

Unanswered research questions relating to epithelial cell biology and IBD
Sean P. Colgan, PhD and Lloyd Mayer, MD

Unanswered research questions relating to adaptive and regulatory immune responses
Charles O. Elson, III, MD and Ivan J. Fuss, MD
Unanswered research questions relating to microbial-host interactions
Wayne I. Lencer, MD and R. Balfour Sartor, MD

11:10 am—Move to second breakout

11:30 am

Unanswered research questions relating to epithelial cell biology and IBD
Sean P. Colgan, PhD and Lloyd Mayer, MD

Unanswered research questions relating to adaptive and regulatory
immune responses
Charles O. Elson, III, MD and Ivan J. Fuss, MD
Unanswered research questions relating to microbial-host interactions
Wayne I. Lencer, MD and R. Balfour Sartor, MD

12:20 pm Lunch break

*Session VII B: State-of-the-art in inflammation and cell activation of IBD
Moderators: Sean P. Colgan, PhD and Ivan J. Fuss, MD

2:00 pm
Novel pathogenetic paradigms in IBD
Sean P. Colgan, PhD

2:20 pm
Does the IL23/Th17 axis play a role in IBD pathogensis?
Casey T. Weaver, MD

2:40 pm
Are NKT cells relevant in IBD?
Ivan J. Fuss, MD

3:00 pm
Mechanisms regulating innate immune cells activation in IBD
Christian Jobin, PhD

3:20 pm
Panel discussion

3:45 pm
Coffee break and poster viewing

*Session VIII B: Basic research scientific presentations–II
Moderators: Matthew Grisham, PhD and Scott Plevy, MD

4:00 pm
Presentation of basic science research abstracts

5:30 pm
Adjourn

SUNDAY, DECEMBER 7, 2008

7:00 am
Breakfast

8:00 am
Welcome and introduction
Lloyd Mayer, MD and R. Balfour Sartor, MD

*Session IX B: State-of-the-art in immunology of IBD–II
Moderators: Jonathan Braun, MD, PhD and Casey T. Weaver, MD

8:10 am
A review of animal models in IBD
Matthew Grisham, PhD

8:30 am
Cell signaling pathways that regulate colitis in animal models
Scott B. Snapper, MD, PhD

8:50 am
New insights into the role of B cells in IBD
Jonathan Braun, MD, PhD

9:10 am
What role does intestinal permeability and epithelial cell barrier
function play in IBD?
Jerrold R. Turner, MD, PhD

9:30 am
Panel discussion

10:00 am
Coffee break

*Session X B: Basic research scientific presentations–III

Moderators: Wayne I. Lencer, MD and Hans-Christian Reinecker, MD, PhD

10:30 am
Presentation of basic scientific research abstracts

12:00 pm
Summary and adjourn
Wayne I. Lencer, MD and Hans-Christian Reinecker, MD, PhD

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